BioPerine
Snapshot
BioPerine is a patented black pepper extract standardized to 95% piperine, known for significantly enhancing the absorption and bioavailability of nutrients, herbs, and supplements.
What is BioPerine?
BioPerine is a clinically studied, trademarked extract derived from black pepper fruit (Piper nigrum), standardized to contain 95% piperine. Unlike raw black pepper, BioPerine is specifically designed to improve the body's ability to absorb key nutrients—particularly fat-soluble vitamins, amino acids, and plant extracts like curcumin.
Where It Comes From
BioPerine is sourced from the dried fruit of the black pepper vine. It is purified and concentrated under strict quality control standards by Sabinsa Corporation, making it one of the most widely used and clinically validated bioenhancers in the supplement industry.
Key Nutrients & Compounds
The primary compound in BioPerine is piperine, an alkaloid responsible for black pepper’s pungency and its potent absorption-enhancing effects. Piperine increases thermogenesis and stimulates digestive enzymes, which helps the body assimilate nutrients more efficiently.
Health Benefits
BioPerine enhances the absorption of various nutrients and herbal compounds, including curcumin, resveratrol, coenzyme Q10, selenium, and vitamins A, C, D, E, and B-complex. This makes supplements significantly more effective. It may also support metabolic function, promote thermogenesis (the body's fat-burning process), and offer mild antioxidant benefits. Piperine has shown some potential in modulating inflammation and improving cognitive function when used alongside nootropic compounds.
Recommended Dosage
Standard dosage ranges from 5 mg to 10 mg per day when used to enhance nutrient absorption. It is typically included in multi-ingredient formulas rather than taken alone.
How to Use It
BioPerine is commonly found in capsule-based supplements, especially when paired with poorly absorbed compounds like turmeric (curcumin). It should be taken with food or fat-soluble nutrients to maximize absorption. Avoid combining it with medications unless directed by a healthcare provider, as it may also enhance drug bioavailability.
Who Should Use It?
Recommended for individuals taking supplements with nutrients or herbs that have low natural absorption, such as turmeric, resveratrol, or CoQ10. It's especially beneficial for those seeking more efficacy from their supplement regimen without increasing dosages.
Possible Interactions or Cautions
BioPerine can affect the metabolism of certain medications by altering liver enzyme activity. Those on prescription drugs should consult with a healthcare professional before use. Mild gastrointestinal sensitivity may occur in some users at higher doses.
Final Thoughts
BioPerine is a smart and effective addition to any supplement stack, maximizing the benefits of other nutrients by improving their absorption. Its role as a bioavailability enhancer is backed by strong clinical data, making it a staple in premium formulations.
Scientific Studies
Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica, 64(4), 353–356. https://doi.org/10.1055/s-2006-957450
Badmaev, V., et al. (1999). Piperine derived from black pepper increases serum response of beta-carotene during 14 days of oral supplementation. Nutrition Research, 19(3), 381–388. https://doi.org/10.1016/S0271-5317(98)00107-7
Wattanathorn, J., et al. (2008). Piperine, a potential functional food for mood and cognitive disorders. Food and Chemical Toxicology, 46(9), 3106–3110. https://doi.org/10.1016/j.fct.2008.06.024