Shiitake Extract
Shiitake Extract
Snapshot
Shiitake Extract is derived from the edible mushroom Lentinula edodes, providing bioactive compounds like lentinan and eritadenine that support immune function, cardiovascular health, and overall well‑being.
What is Shiitake Extract?
Shiitake Extract is a concentrated form of compounds obtained from the fruiting bodies of the shiitake mushroom. It contains polysaccharides, sterols, and peptides that have been recognized for their immunomodulatory and lipid‑lowering properties.
Where It Comes From
Fresh shiitake mushrooms are harvested at peak maturity, cleaned, and subjected to hot‑water extraction to isolate water‑soluble polysaccharides. The extract is then filtered, concentrated, and spray‑dried into a fine powder standardized for key actives such as lentinan.
Key Nutrients & Compounds
Provides beta‑glucan polysaccharides (notably lentinan), eritadenine, eritadenosine, and various bioactive sterols and amino acids that synergistically support health.
Health Benefits
Shiitake Extract enhances innate and adaptive immunity by activating macrophages and natural killer cells; supports healthy cholesterol levels through eritadenine‑mediated lipid metabolism; exhibits antioxidant activity that protects cells from oxidative stress; and may aid in healthy liver function.
Recommended Dosage
Typical dosing ranges from 500 mg to 2 g of standardized shiitake extract daily, often divided into one or two servings. Standardization usually ensures 10–20% polysaccharide content; adjust dosage based on product specifications.
How to Use It
Mix the powder into warm water, tea, or broth, or take in capsule form with meals to enhance absorption. Start at the lower end of the dosing range and increase gradually based on tolerance and desired effect.
Who Should Use It?
Ideal for individuals seeking natural immune support, those aiming to maintain healthy blood lipid profiles, or anyone looking to incorporate functional mushrooms into their wellness routine.
Possible Interactions or Cautions
Generally well tolerated. Use caution if taking immunosuppressive medications or anticoagulants due to potential additive effects. Rarely, high doses may cause mild digestive discomfort; discontinue if adverse reactions occur.
Final Thoughts
Shiitake Extract offers a potent, natural source of immune‑modulating and lipid‑supporting compounds. Its multifaceted benefits make it a valuable addition to daily health regimens when used consistently and responsibly.
Scientific Studies
Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19(1):65–96. https://doi.org/10.1615/critrevimmunol.v19.i1.40
Sugiyama K, Akachi T, Yamakawa A. Hypocholesterolemic action of eritadenine is mediated by a modification of hepatic phospholipid metabolism in rats. J Nutr. 1995;125(8):2134–2144. https://doi.org/10.1093/jn/125.8.2134
Mori K, Obata T, Nakasone T, Terashima T. Immunomodulatory effects of lentinan on human peripheral blood mononuclear cells in vitro. Cancer Lett. 1985;28(1):35–40. https://doi.org/10.1016/0304-3835(85)90044-3