Turkey Tail Extract
Turkey Tail Extract
Snapshot
Turkey Tail Extract is a concentrated mushroom supplement from Trametes versicolor fruiting bodies, rich in polysaccharopeptides that support immune modulation, gut health, and antioxidant defenses.
What is Turkey Tail Extract?
Turkey Tail Extract is derived from the fruiting bodies of the Trametes versicolor fungus, commonly known as Turkey Tail mushroom. It concentrates bioactive polysaccharopeptides—primarily PSK (Krestin) and PSP—that enhance immune cell activity and balance microbiota.
Where It Comes From
Mature Turkey Tail mushrooms are sustainably harvested or cultivated, cleaned, and subjected to hot‑water extraction to isolate water‑soluble polysaccharides. The extract is filtered, concentrated, and spray‑dried into a fine powder standardized for PSK and PSP content.
Key Nutrients & Compounds
Provides polysaccharide‑K (PSK), polysaccharopeptide (PSP), beta‑glucans, and trace phenolic compounds that synergize to modulate innate and adaptive immune responses.
Health Benefits
Turkey Tail Extract enhances natural killer cell and macrophage activity; supports balanced cytokine production; promotes healthy gut microbiota by acting as a prebiotic; and offers antioxidant protection that mitigates oxidative stress.
Recommended Dosage
Typical dosing ranges from 1 g to 3 g of extract daily, divided into two or three servings with meals. Cancer support protocols often use 3 g daily of PSK‑standardized extract under clinical guidance.
How to Use It
Mix the powder into hot water, tea, coffee, or smoothies. Capsules can be taken with a meal to optimize absorption. Begin with lower doses and increase gradually to assess tolerance.
Who Should Use It?
Ideal for individuals seeking to support immune resilience, those recovering from illness, or anyone aiming to balance gut flora. Clinical use of PSK for adjunct cancer therapy should follow medical supervision.
Possible Interactions or Cautions
Generally well tolerated. Rare gastrointestinal discomfort may occur. Use caution if on immunosuppressive medications; consult a healthcare provider before combining with prescription therapies.
Final Thoughts
Turkey Tail Extract is a well‑researched medicinal mushroom offering multifaceted immune and gut support. Its synergy of PSK, PSP, and beta‑glucans makes it a valuable adjunct in wellness and therapeutic protocols.
Scientific Studies
Fukuzawa T, et al. Enhancement of immune functions by administration of Trametes versicolor extract in healthy volunteers. Int J Immunopharmacol. 1996;18(12):857–865. https://doi.org/10.1016/S0192-0561(96)00076-8
Ooi VEC, Liu F. Immunomodulation and anticancer activity of polysaccharide‑protein complexes. Curr Med Chem. 2000;7(7):715–729. https://doi.org/10.2174/0929867003373365
Mizuno T, et al. Antitumor polysaccharide from Coriolus versicolor (Turkey Tail): clinical efficacy and safety in cancer patients. Jpn J Complement Altern Med. 2008;5(2):147–153.