Chrysin
Chrysin
Snapshot
Chrysin is a natural flavonoid known for its antioxidant, anti-inflammatory, and potential testosterone-supporting properties.
What is Chrysin?
Chrysin (5,7-dihydroxyflavone) is a naturally occurring flavonoid found in honey, passionflower, and propolis. It's primarily recognized for its potential to modulate hormones, especially its claimed ability to inhibit aromatase—an enzyme responsible for converting testosterone into estrogen.
Where It Comes From
Chrysin is most commonly sourced from passionflower (Passiflora caerulea) and bee propolis. It can also be synthetically produced for use in dietary supplements, often marketed in formulas aimed at muscle building or male vitality.
Key Nutrients & Compounds
As a flavonoid, chrysin provides powerful antioxidant support, helping combat oxidative stress in the body. It interacts with enzymes like aromatase, which has made it of interest in testosterone-enhancing and estrogen-lowering supplement formulas.
Health Benefits
Chrysin may support testosterone balance by potentially reducing estrogen conversion, making it popular among athletes and bodybuilders. It also offers antioxidant and anti-inflammatory benefits that may contribute to cardiovascular and immune health. Some early studies suggest it may have anti-anxiety effects through modulation of GABA receptors in the brain.
Recommended Dosage
Supplement dosages typically range from 500 mg to 1,000 mg per day. However, chrysin's low oral bioavailability means it's often paired with bioenhancers or taken in liposomal or topical forms for improved absorption.
How to Use It
Chrysin is available in capsules, tablets, and powders, and sometimes as part of testosterone booster blends. It may also be found in topical creams designed for direct skin absorption.
Who Should Use It?
Chrysin may be beneficial for men seeking natural hormone support, individuals managing oxidative stress, or those looking for a natural anti-inflammatory compound. Athletes and bodybuilders are the most common users.
Possible Interactions or Cautions
Due to its hormone-modulating properties, chrysin may not be suitable for individuals with hormone-sensitive conditions. Pregnant or breastfeeding women should avoid it, and anyone considering long-term use should consult a healthcare provider.
Final Thoughts
While promising as a natural testosterone and estrogen-balancing agent, chrysin’s effectiveness may be limited without enhanced delivery methods. Still, it holds value as an antioxidant and hormone-modulating compound with growing interest in the fitness and wellness communities.
Scientific Studies
Zingue, S., et al. (2013). Anti-aromatase and antiestrogenic activities of flavonoids from Dorstenia psilurus. Fitoterapia, 91, 121–126. https://doi.org/10.1016/j.fitote.2013.08.005
Sahebkar, A. (2015). A systematic review and meta-analysis on the effect of flavonoids on testosterone levels. Journal of Dietary Supplements, 12(3), 273–288. https://doi.org/10.3109/19390211.2014.935501
Ghosh, D., & Scheepens, A. (2009). Vascular action of polyphenols. Molecular Nutrition & Food Research, 53(3), 322–331. https://doi.org/10.1002/mnfr.200800182