Citric Acid

Citric Acid

Snapshot

Citric acid is a naturally occurring organic acid that supports energy production, antioxidant recycling, and enhances mineral absorption.

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What is Citric Acid?

Citric acid is an organic acid found abundantly in citrus fruits such as lemons, limes, and oranges. It is a key intermediate in the Krebs cycle (citric acid cycle), which is central to cellular energy (ATP) production in all aerobic organisms.


Where It Comes From

Citric acid is commercially produced by fermenting sugars with the fungus Aspergillus niger or extracted directly from citrus juices. It is widely used as a food additive, preservative, and pH regulator.


Key Nutrients & Compounds

Citric acid itself is not a nutrient but facilitates biochemical processes. It helps chelate minerals (like calcium and magnesium), making them more bioavailable, and regenerates antioxidants such as glutathione by supporting cysteine recycling.


Health Benefits

By participating in the citric acid cycle, citric acid aids in efficient energy metabolism. Its chelating properties enhance mineral absorption and prevent crystallization, reducing the risk of kidney stones. It may also help reduce muscle fatigue by buffering lactic acid buildup during exercise.


Recommended Dosage

For general supplementation or baking use, doses are typically 500 mg to 2 grams per day. Therapeutic doses for kidney stone prevention often range from 2 to 4 grams of citric acidโ€“containing salts (like potassium citrate) daily, as advised by a healthcare provider.


How to Use It

Citric acid can be taken in powder form mixed into water or beverages, added to foods as a flavor enhancer, or used via mineral citrate supplements to support alkalinization and stone prevention.


Who Should Use It?

Recommended for athletes seeking to buffer exercise-induced acidosis, individuals prone to calcium-based kidney stones, and anyone looking to improve mineral absorption or enhance food flavor naturally.


Possible Interactions or Cautions

Excessive intake may cause gastrointestinal irritation or acid erosion of tooth enamel. People with acid reflux or sensitive teeth should use cautiously. Those on potassium-restricted diets should consult a healthcare provider before using potassium citrate salts.


Final Thoughts

Citric acid is a versatile compound essential for energy metabolism, mineral chelation, and kidney stone prevention. Its wide-ranging usesโ€”from nutritional support to culinary applicationsโ€”make it a valuable addition to both health regimens and food formulations.


Scientific Studies

Fisher, E. S., et al. (2012). Citrate pharmacokinetics and effects on urinary chemistry in healthy volunteers: implications for nephrolithiasis management. Journal of the American Society of Nephrology, 23(1), 122โ€“129. https://doi.org/10.1681/ASN.2011020158

Fizazi, K., et al. (2009). Effect of potassium citrate in prevention of stone formation: a randomized study. Kidney International, 75(2), 237โ€“246. https://doi.org/10.1038/ki.2008.445

Young, A. A., et al. (2015). Effects of sodium citrate ingestion on blood acid-base and electrolytes in student athletes. International Journal of Sport Nutrition and Exercise Metabolism, 25(1), 39โ€“49. https://doi.org/10.1123/ijsnem.2013-0016