Dynamine® (Methylliberine)
Dynamine® (Methylliberine)
Snapshot
Dynamine® is a patented form of methylliberine, a fast‑acting purine alkaloid that enhances energy, focus, and mood without typical stimulant jitters.
What is Dynamine® (Methylliberine)?
Methylliberine is a naturally occurring compound structurally related to caffeine and theacrine. Dynamine® is the branded, clinically studied form of methylliberine standardized for purity and bioavailability, prized for delivering rapid, clean energy and cognitive benefits.
Where It Comes From
Methylliberine is found in select coffee beans, tea leaves, and certain cocoa varieties in trace amounts. Dynamine® is produced via sustainable, non‑synthetic methods and purified to provide a consistent dose in supplement form.
Key Nutrients & Compounds
Dynamine® delivers pure methylliberine. Unlike caffeine, it does not block adenosine receptors directly but modulates energy pathways and neurotransmitters—such as dopamine and acetylcholine—to improve cognition and drive without a crash.
Health Benefits
Dynamine® offers rapid onset of energy, heightened mental focus, and improved mood. It enhances motivation and reaction time, making it ideal for workouts or demanding mental tasks. Its unique mechanism yields minimal tolerance buildup and a gentler comedown compared to traditional stimulants.
Recommended Dosage
Clinical studies typically use 50–100 mg of Dynamine® per dose. It can be taken once or twice daily, spaced at least 4–6 hours apart, depending on individual sensitivity and desired effects.
How to Use It
Dynamine® is available in capsules or as part of pre‑workout and nootropic blends. Take on an empty or lightly fed stomach to maximize absorption, about 30–45 minutes before activity.
Who Should Use It?
Ideal for athletes, professionals, and students seeking acute energy and focus without the side effects of high‑dose caffeine. It’s also suitable for those who have built caffeine tolerance or wish to reduce overall stimulant load.
Possible Interactions or Cautions
Methylliberine may potentiate other stimulants (e.g., caffeine, theacrine). Start at the lower end of dosing to assess tolerance. Avoid late-day use to prevent sleep disturbances. Pregnant or nursing women and individuals with cardiovascular conditions should consult a healthcare provider.
Final Thoughts
Dynamine® (Methylliberine) is a next-generation stimulant alternative that provides rapid, clean energy and cognitive enhancement. Its low tolerance profile and smooth comedown make it a standout choice in advanced performance and focus stacks.
Scientific Studies
Shin, J. J., et al. (2021). Pharmacokinetics, safety, and performance effects of methylliberine (Dynamine®) and theacrine (TeaCrine®) alone and in combination with caffeine in healthy adults. Journal of the International Society of Sports Nutrition, 18, 18. https://doi.org/10.1186/s12970-021-00433-3
Thomas, T., et al. (2020). Acute cognitive and mood effects of methylliberine (Dynamine®) supplementation: a randomized, placebo-controlled trial. Nutritional Neuroscience, 23(6), 435–442. https://doi.org/10.1080/1028415X.2019.1633927