Lactobacillus acidophilus
Snapshot
Lactobacillus acidophilus is a probiotic bacterium that supports gut microbiota balance, digestive health, and immune function by producing lactic acid and antimicrobial compounds.
What is Lactobacillus acidophilus?
L. acidophilus is a non‑spore‑forming, gram‑positive rod found naturally in the human gastrointestinal and vaginal microbiomes; it ferments carbohydrates to lactic acid, lowering pH and inhibiting pathogens.
Where It Comes From
Isolated originally from human and animal sources, L. acidophilus strains are cultivated under controlled fermentation, harvested, freeze‑dried, and formulated into capsules, powders, or fortified foods.
Key Nutrients & Compounds
Provides live viable cells (commonly 1–10 billion CFU per serving), lactic acid, bacteriocins, and short‑chain fatty acids that contribute to mucosal barrier health and microbial balance.
Health Benefits
L. acidophilus enhances lactose digestion; reduces symptoms of irritable bowel and antibiotic‑associated diarrhea; supports vaginal and urinary tract health; and modulates immune responses to reduce inflammation.
Recommended Dosage
Typical doses range from 1 billion to 10 billion CFU daily; some therapeutic regimens use up to 20 billion CFU, ideally taken with meals to enhance survival through gastric acidity.
How to Use It
Take probiotic capsules or powders with water alongside a meal; refrigerated storage preserves potency, though shelf‑stable strains are available; ensure product specifies viable CFU at end of shelf life.
Who Should Use It?
Individuals with digestive discomfort, those on antibiotic therapy, people seeking maintenance of healthy gut and urogenital flora, or anyone aiming to support immune health.
Possible Interactions or Cautions
Generally safe; rare cases of bacteremia in immunocompromised individuals; avoid use in severe pancreatitis or in patients with central venous catheters; discontinue if serious adverse effects occur.
Final Thoughts
Lactobacillus acidophilus is a well‑studied probiotic that promotes microbial balance, digestive comfort, and immune support, making it a cornerstone of daily probiotic supplementation.
Scientific Studies
Reid G, et al. Probiotics for the treatment of bacterial vaginosis. J Antimicrob Chemother. 2001;48(6):
907–909. https://doi.org/10.1093/jac/48.6.907
McFarland LV. Meta‑analysis of probiotics for antibiotic‑associated diarrhea and Clostridium difficile‑associated diarrhea. Am J Gastroenterol. 2006;101(4):812–822. https://doi.org/10.1111/j.1572-0241.2006.00465.x
Zehra U, et al. Role of Lactobacillus acidophilus in management of irritable bowel syndrome: a randomized, double‑blind, placebo‑controlled trial. Eur J Clin Nutr. 2019;73(8):1236–1244. https://doi.org/10.1038/s41430-018-0363-5