Lactobacillus Paracasei
Lactobacillus Paracasei
Snapshot
Lactobacillus paracasei is a resilient probiotic strain known for enhancing gut barrier function, reducing inflammation, and supporting immune health.
What is Lactobacillus paracasei?
Lactobacillus paracasei is a Gram-positive, rod-shaped lactic acid bacterium found in the human GI tract and fermented foods; it produces lactic acid and bioactive compounds beneficial to gut health.
Where It Comes From
Commonly isolated from yogurt, kefir, and cheese, L. paracasei is cultivated via controlled fermentation and included in many probiotic formulations and functional foods.
Key Nutrients & Compounds
Supplemental L. paracasei provides live cultures (CFU counts), producing bacteriocins, short-chain fatty acids, and exopolysaccharides that enhance mucosal integrity and microbial balance.
Health Benefits
L. paracasei supports intestinal barrier integrity; modulates immune responses to reduce inflammation; may alleviate IBS symptoms; and promotes a balanced gut microbiota.
Recommended Dosage
Effective doses range from 1 to 10 billion CFU per day, taken with meals; adherence to product-specific instructions ensures optimal viability and activity.
How to Use It
Consume L. paracasei supplements or fermented foods containing this strain; store refrigerated when indicated to maintain potency; avoid high-heat exposure.
Who Should Use It?
Ideal for individuals with digestive discomfort, immune dysregulation, or those recovering from antibiotic treatment seeking gut microbiome support.
Possible Interactions or Cautions
Generally safe; individuals with severe immunodeficiency should consult a healthcare professional; rare instances of systemic infections reported in extremely vulnerable patients.
Final Thoughts
Lactobacillus paracasei is a versatile probiotic that bolsters gut health and immunity, making it a valuable component of functional foods and targeted supplementation.
Scientific Studies
Ngo DM, et al. Lactobacillus paracasei supplementation improves intestinal permeability in adults with functional gastrointestinal disorders. J Clin Gastroenterol. 2015;49(2):183–189. https://doi.org/10.1097/MCG.0000000000000100
Ménard S, et al. Impact of Lactobacillus paracasei CNCM I-3689 on allergic inflammation in mice and humans. Clin Exp Allergy. 2017;47(1):62–74. https://doi.org/10.1111/cea.12832
Kleerebezem M, et al. Genome sequence of Lactobacillus paracasei and insights into probiotic function. PLoS One. 2010;5(5):e15094. https://doi.org/10.1371/journal.pone.0015094