Raspberry Ketone
Raspberry Ketone
Snapshot
Raspberry Ketone is a natural phenolic compound used to support fat metabolism and weight management by modulating adiponectin levels and lipolysis.
What is Raspberry Ketone?
Raspberry Ketone (4‑(4‑hydroxyphenyl)‑2‑butanone) is a volatile aroma compound originally identified in red raspberries, now synthesized for use in dietary supplements.
Where It Comes From
Naturally occurring in red raspberry fruit; supplemental Raspberry Ketone is typically produced via chemical synthesis or biotechnological methods to supply consistent, high‑purity powder.
Key Nutrients & Compounds
Provides the pure ketone molecule that has been shown in preclinical studies to increase adiponectin secretion, enhance lipid breakdown enzymes, and exhibit antioxidant activity.
Health Benefits
Raspberry Ketone may support healthy weight management by elevating adiponectin levels, promoting fatty acid oxidation, and potentially reducing adipose tissue accumulation. Antioxidant properties may also protect against oxidative stress.
Recommended Dosage
Typical supplemental doses range from 100 mg to 200 mg daily, often taken in divided doses; follow product‑specific recommendations and consult a healthcare provider for personalized guidance.
How to Use It
Take Raspberry Ketone capsules or powder with water, preferably in the morning and early afternoon to coincide with active metabolism; can be combined with meals or thermogenic blends.
Who Should Use It?
Adults seeking to support healthy body composition and metabolic function as part of a balanced diet and exercise regimen; not recommended for pregnant or breastfeeding individuals.
Possible Interactions or Cautions
Limited human safety data; high doses may cause jitteriness, tachycardia, or gastrointestinal upset. Avoid use with stimulants or in individuals with cardiovascular conditions.
Final Thoughts
While preclinical findings on Raspberry Ketone are promising for metabolic support, robust human trials are needed. Use conservatively within recommended dosages and as part of an overall healthy lifestyle.
Scientific Studies
Morimoto C, et al. Dietary administration of raspberry ketone-rich extract increases adiponectin secretion and attenuates weight gain in mice. J Nutr Biochem. 2005;16(10):619–626. https://doi.org/10.1016/j.jnutbio.2005.03.003
Tsuda T. Dietary anthocyanin‑rich extracts improve adipocyte function and obesity‑related disorders. J Nutr Sci Vitaminol (Tokyo). 2008;54(2):150–153. https://doi.org/10.3177/jnsv.54.150
Kawada T, et al. Inhibitory effects of raspberry ketone on adipogenesis in 3T3‑L1 cells. Biol Pharm Bull. 2006;29(3):441–445. https://doi.org/10.1248/bpb.29.441